@jwcph
For vst you could try reaper. But there are quite a few audio plugin systems for linux.
Davinci yeah because of the GPU reqs you either need to use iommu to assign the GPU to the VM or run it baremetal.
For affinity you might need to make some wine tweaks
https://codeberg.org/Wanesty/affinity-wine-docs
Or there are alts
https://alternativeto.net/software/affinity-designer/?license=free